1.
Cleve Clin J Med
; 91(2): 109-117, 2024 Feb 02.
Article
in English
| MEDLINE
| ID: mdl-38307604
ABSTRACT
Venous thromboembolism (VTE) is a major health burden in patients with cancer, causing morbidity, emergency room visits, hospitalizations, and death. Treatment is challenging, as it is necessary to balance the risk of recurrent thrombosis and bleeding associated with anticoagulants. Treatment paradigms are shifting from low-molecular-weight heparin monotherapy. Multiple recent randomized controlled trials have demonstrated the safety and efficacy of direct oral anticoagulants in this setting. Current studies are evaluating factor XI inhibitors as potential treatments for cancer-associated VTE.
Subject(s)
Neoplasms , Venous Thromboembolism , Humans , Venous Thromboembolism/drug therapy , Venous Thromboembolism/etiology , Anticoagulants/therapeutic use , Heparin, Low-Molecular-Weight/therapeutic use , Neoplasms/complications , Neoplasms/therapy , Hemorrhage/chemically induced , Hemorrhage/complications
2.
Eur J Intern Med
; 74: 5-7, 2020 04.
Article
in English
| MEDLINE
| ID: mdl-32094020